Gastric PCO(2) monitoring system based on a double membrane type PCO(2) sensor

Tetsushi Sekiguchi*, Yuko Nagai, Tetsuya Makino, Kohei Ohno, Michihiro Nakamura, Hidehiro Hosaka, Hideaki Sakio, Satoshi Ohtsu, Hiroyuki Takahashi


研究成果: Article査読

6 被引用数 (Scopus)


Gastric PCO(2) monitoring during canine hemorrhagic shock encountered occasional baseline drift to higher direction when conventional PCO(2) sensor was used. As a result of chemical analysis of gastric juice of dogs and human, hydrogen sulfide and acetic acid were identified as causative compounds. It was speculated that these weak acid molecules would permeate gas-permeable silicone membrane to be accumulated in the inner solution of Severinghaus-type PCO(2) sensors. In order to prevent this phenomenon, double-membrane type PCO(2) sensor was constructed. In this sensor, acid-neutralizing solution was installed between the inner and the outer membranes in order to dissociate weak acid molecules into corresponding ions, which can not diffuse into the inner silicone membrane. In addition, Cu2O particles were mixed in the inner silicone membrane to trap hydrogen sulfide in this membrane. It was confirmed by experiments in vitro that the readings of improved gastric PCO(2) sensors were not affected by acetic acid or hydrogen sulfide. As a result of a preliminary clinical evaluation, continuous monitoring of gastric PCO(2) was carried out for 72 h without detectable baseline drift or the change of sensitivity.

ジャーナルSensors and Actuators, B: Chemical
49 B49
出版ステータスPublished - 1998

ASJC Scopus subject areas

  • 電子材料、光学材料、および磁性材料
  • 器械工学
  • 凝縮系物理学
  • 表面、皮膜および薄膜
  • 金属および合金
  • 電子工学および電気工学
  • 材料化学


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