GnIH control of feeding and reproductive behaviors

Kazuyoshi Tsutsui, Takayoshi Ubuka

    研究成果: Review article査読

    32 被引用数 (Scopus)


    In 2000, Tsutsui and colleagues discovered a neuropeptide gonadotropin-inhibitory hormone (GnIH) that inhibits gonadotropin release in birds. Subsequently, extensive studies during the last 15 years have demonstrated that GnIH is a key neurohormone that regulates reproduction in vertebrates, acting in the brain and on the pituitary to modulate reproduction and reproductive behavior. On the other hand, deprivation of food and other metabolic challenges inhibit the reproductive axis as well as sexual motivation. Interestingly, recent studies have further indicated that GnIH controls feeding behavior in vertebrates, such as in birds and mammals. This review summarizes the discovery of GnIH and its conservation in vertebrates and the neuroendocrine control of feeding behavior and reproductive behavior by GnIH.

    ジャーナルFrontiers in Endocrinology
    出版ステータスPublished - 2016

    ASJC Scopus subject areas

    • Endocrinology, Diabetes and Metabolism

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