Habitual exercise decreases plasma xanthine oxidoreductase activity in middle-Aged and older women

Keisei Kosaki, Atsuko Kamijo-Ikemori, Takeshi Sugaya, Koichiro Tanahashi, Nobuhiko Akazawa, Chihiro Hibi, Takashi Nakamura, Takayo Murase, Kenjiro Kimura, Yugo Shibagaki, Seiji Maeda*

*この研究の対応する著者

研究成果査読

1 被引用数 (Scopus)

抄録

The aim of present study was to investigate the association plasma xanthine oxidoreductase activity, which has gained attention as a novel preventive target of cardiovascular disease, and various physiological parameters and was to determine the effects of habitual exercise on plasma xanthine oxidoreductase activity in middle-Aged and older women. In the cross-sectional study, we investigated the association between plasma xanthine oxidoreductase activity and various physiological parameters in 94 middle-Aged and older women. In the interventional study, subjects (n = 22) were divided into two groups: exercise (n = 12) or the control group (n = 10), whereby we examined the effect of 12-week aerobic exercise training on plasma xanthine oxidoreduc- tase activity in middle-Aged and older women. The cross-sectional study demonstrated that plasma xanthine oxidoreductase activity was significantly associated with various physiological parameters, including visceral fat and daily step counts. In the interventional study, the plasma xanthine oxidoreductase activity significantly decreased after the 12-week aerobic exercise training, its changes were inversely associated with the changes in daily step counts. Our results revealed that the plasma xanthine oxidoreductase activity was associated with visceral fat accumulation and lack of exercise, and it was decreased by the aerobic exercise training.

本文言語English
ページ(範囲)247-253
ページ数7
ジャーナルJournal of Clinical Biochemistry and Nutrition
62
3
DOI
出版ステータスPublished - 2018
外部発表はい

ASJC Scopus subject areas

  • 医学(その他)
  • 栄養および糖尿病
  • 臨床生化学

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