Haemostatic effects of fibrinogen y chain dodecapeptide-conjugates as platelet substitutes

Yosuke Okamura, Ippei Maekawa, Toshinori Fujie, Shinji Takeoka, Makoto Handa, Yasuo Ikeda

研究成果: Paper査読

抄録

We have studied prototypes of platelet substitutes by conjugating the dodecapeptide (H12); a part of the amino acid sequence of fibrinogen, to the surface of polymerized albumin particles (polyAlb) or phospholipid vesicles (vesicle). Both H12-polyAlb and H12-vesicle showed a hemostatic effect, based on the analysis of the tail bleeding time of thrombocytopenic rats. The H12-polyAlb was more effective than the H12-vesicle.

本文言語English
ページ数1
出版ステータスPublished - 2005 12 1
イベント54th SPSJ Annual Meeting 2005 - Yokohama, Japan
継続期間: 2005 5 252005 5 27

Conference

Conference54th SPSJ Annual Meeting 2005
CountryJapan
CityYokohama
Period05/5/2505/5/27

ASJC Scopus subject areas

  • Engineering(all)

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