TY - JOUR
T1 - Helix-coil transition and 1/f fluctuation in a polypeptide
AU - Takano, Mitsunori
AU - Takahashi, Takuya
AU - Nagayama, Kuniaki
PY - 1998
Y1 - 1998
N2 - We report on molecular dynamics simulations of the helix-coil transition of a polypeptide. The simulated transition was two-state-like and similar to the solid-liquid-like transition that has been observed in computer simulations of an atomic cluster. At the transition temperature, the polypeptide chain fluctuated between a helical and a random-coil state, and we observed 1/f fluctuation through potential-energy fluctuations. The origin of the observed 1/f fluctuation is discussed, considering the underlying potential-energy landscape.
AB - We report on molecular dynamics simulations of the helix-coil transition of a polypeptide. The simulated transition was two-state-like and similar to the solid-liquid-like transition that has been observed in computer simulations of an atomic cluster. At the transition temperature, the polypeptide chain fluctuated between a helical and a random-coil state, and we observed 1/f fluctuation through potential-energy fluctuations. The origin of the observed 1/f fluctuation is discussed, considering the underlying potential-energy landscape.
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U2 - 10.1103/PhysRevLett.80.5691
DO - 10.1103/PhysRevLett.80.5691
M3 - Article
AN - SCOPUS:0000546668
SN - 0031-9007
VL - 80
SP - 5691
EP - 5694
JO - Physical Review Letters
JF - Physical Review Letters
IS - 25
ER -