High-content analysis of single cells using a wide-field imaging sensor

T. Tanaka, T. Yoshino, Y. Maeda, T. Saeki, R. Negishi, R. Iwata, A. Kogiso, H. Dobashi, Tadashi Matsunaga

研究成果: Conference contribution

抄録

Electrochemical sensing systems have been utilized in biosensors because it is easy to integrate the electrodes and electric circuits on miniaturized devices. In contrast, it was hard to integrate photo-sensing systems consisting of advanced optical components (e.g., condensing lenses and optical filters) in small devices due to the difficulties in miniaturization and cost-cutting of those optical components. However, recent efforts overcame this technical barrier, and thus a huge number of two-dimensional (2D) photosensors are equipped in digital cameras and smartphones, and widely used around the world. Technical development of such photosensors led to creation of novel biosensing systems enabling rapid, sensitive, and easy detection of biomolecules and microorganisms. This article summarized our recent achievement on wide-field imaging-based biosensors in which complementary metal oxide semiconductor (CMOS) image sensors were used for detection of various biological objects. In particular, high content analysis of single cells based on the developed photo-biosensing systems is introduced.

本文言語English
ホスト出版物のタイトルChemical Sensors 12
ホスト出版物のサブタイトルChemical and Biological Sensors and Analytical Systems
出版社Electrochemical Society Inc.
ページ139-146
ページ数8
75
16
ISBN(電子版)9781607685395
DOI
出版ステータスPublished - 2016
外部発表はい
イベントSymposium on Chemical Sensors 12: Chemical and Biological Sensors and Analytical Systems - PRiME 2016/230th ECS Meeting - Honolulu, United States
継続期間: 2016 10 22016 10 7

Other

OtherSymposium on Chemical Sensors 12: Chemical and Biological Sensors and Analytical Systems - PRiME 2016/230th ECS Meeting
国/地域United States
CityHonolulu
Period16/10/216/10/7

ASJC Scopus subject areas

  • 工学(全般)

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