High frequency activities in the human orbitofrontal cortex in sleep-wake cycle

Masaki Nishida*, Sunao Uchida, Nobuhide Hirai, Fumikazu Miwakeichi, Taketoshi Maehara, Kensuke Kawai, Hiroyuki Shimizu, Satoshi Kato

*この研究の対応する著者

研究成果: Article査読

15 被引用数 (Scopus)

抄録

We recorded human orbitofrontal electrocorticogram during wakefulness and sleep in epileptic patients using subdural electrodes. During wakefulness and rapid eye movement (REM) sleep, we observed beta activity in the raw orbitofrontal signals. Power spectral analysis demonstrated beta enhancement during wakefulness and REM sleep when compared to slow wave sleep (SWS). During the phasic REM periods, the beta power was significantly lower than during the tonic REM periods. Gamma enhancement manifested itself in four out of six subjects during the phasic periods. This study is the first that has focused on electrical activity in the human orbitofrontal cortex. Although the role of the orbitofrontal cortex during sleep still remains unclear, high frequency activities give us important suggestions in elucidating the human sleep mechanism.

本文言語English
ページ(範囲)110-115
ページ数6
ジャーナルNeuroscience Letters
379
2
DOI
出版ステータスPublished - 2005 5月 6
外部発表はい

ASJC Scopus subject areas

  • 神経科学(全般)

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