This paper reports an application of cycloolefin polymer (ZEONEX) for affinity microchip electrophoresis (AMCE), and an improvement of the detectability for chiral analyses by using a thermal lens microscope (TLM) as a detection scheme and a sweeping technique based on a strong affinity between amino acids and proteins. In the chiral analysis of racemic tryptophan derivatized with a dye on the ZEONEX chip, the affinity sweeping by bovine serum albumin provided a 26-fold sensitivity enhancement compared to a conventional AMCE analysis.
|出版ステータス||Published - 2006 1 1|
|イベント||10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006 - Tokyo, Japan|
継続期間: 2006 11 5 → 2006 11 9
|Conference||10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006|
|Period||06/11/5 → 06/11/9|
ASJC Scopus subject areas
- Chemical Engineering (miscellaneous)