How to ensure safety factors in the development of artificial heart: Verified by the usage of "modeling and simulation" technology

Mitsuo Umezu

研究成果: Conference contribution

1 被引用数 (Scopus)

抄録

The author has involved in two types of clinically available artificial hearts in Japan for these 30 years. Firstly, Toyobo auxiliary pulsatile ventricular assist pump was commercialized in 1991 and over 700 clinical cases are reported in Japanese market. Secondly, an implantable non-pulsatile ventricular assist pump (EVAHEART, Sunmedical Tech. Res. Co.) has been implanted into 11 patients in Japan. The author has been establishing a methodology to eliminate considerable risk factors through a development of hydrodynamic performance test, durability test and biocompatibility test. These in vitro tests are all effective to ensure a safety of the system and also in vitro tests have a contribution to reduce a number of animal experiments.

本文言語English
ホスト出版物のタイトルLife System Modeling and Simulation - International Conference, LSMS 2007, Proceedings
ページ88-96
ページ数9
出版ステータスPublished - 2007 12 1
イベント2007 International Conference on Life System Modeling and Simulation, LSMS 2007 - Shanghai, China
継続期間: 2007 9 142007 9 17

出版物シリーズ

名前Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
4689 LNBI
ISSN(印刷版)0302-9743
ISSN(電子版)1611-3349

Conference

Conference2007 International Conference on Life System Modeling and Simulation, LSMS 2007
CountryChina
CityShanghai
Period07/9/1407/9/17

ASJC Scopus subject areas

  • Theoretical Computer Science
  • Computer Science(all)

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