Human c-fgr gene does not contain coding sequence for actin-like protein

Makoto Nishizawa, Kentaro Semba, Tadashi Yamamoto, Kumao Toyoshima

研究成果: Article査読

2 被引用数 (Scopus)

抄録

fgr is a member of the protein kinase oncogene family and was found to have the highest homology to yes gene among the members of the family. Using a v-yes probe, a molecular clone of human c-fgr locus was isolated from a genomic library. Nucleotide sequence determination revealed that the actin gene-like sequence found in v-fgr gene was absent at the corresponding position of the c-fgr gene. Thus, the v-fgr gene product is considered to be a tri-chimeric gene product consisting of viral gag gene and two distinct cellular genes, actin gene and the proto-fgr gene.

本文言語English
ページ(範囲)155-159
ページ数5
ジャーナルJapanese Journal of Cancer Research GANN
76
3
出版ステータスPublished - 1985 1 1
外部発表はい

ASJC Scopus subject areas

  • 腫瘍学
  • 癌研究

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