Human immunodeficiency virus trans-activator of transcription peptide detection via ribonucleic acid aptamer on aminated diamond biosensor

A. Rahim Ruslinda*, Xianfen Wang, Yoko Ishii, Yuichiro Ishiyama, Kyosuke Tanabe, Hiroshi Kawarada

*この研究の対応する著者

研究成果: Article査読

9 被引用数 (Scopus)

抄録

The potential of ribonucleic acid (RNA) as both informational and ligand binding molecule have opened a scenario in the development of biosensors. An aminated diamond-based RNA aptasensor is presented for human immunodeficiency virus (HIV) trans-activator of transcription (Tat) peptide protein detection that not only gives a labeled or label-free detection method but also provides a reusable platform for a simple, sensitive, and selective detection of proteins. The immobilized procedure was based on the binding interaction between positively charged amine terminated diamond and the RNA aptamer probe molecules with the negatively charged surface carboxylic compound linker molecule such as terephthalic acid.

本文言語English
論文番号123702
ジャーナルApplied Physics Letters
99
12
DOI
出版ステータスPublished - 2011 9月 19

ASJC Scopus subject areas

  • 物理学および天文学(その他)

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