Hypothalamic network for thermoregulatory shivering

K. Kanosue*, Y. H. Zhang, M. Yanase-Fujiwara, T. Hosono

*この研究の対応する著者

研究成果: Article査読

47 被引用数 (Scopus)

抄録

Warming one side of a rat's preoptic area and anterior hypothalamus (POAH) suppresses shivering on both sides of the body, and the present study evaluated the extent to which signals mediating this suppression cross the midline within and below the POAH. Hind paw shivering during unilateral POAH thermal stimulation was measured for rats in which the POAH had been midsagittally transected and for rats in which one side of the hypothalamus had been coronally transected just caudal to the POAH. In midsagittally transected rats, unilateral warming on either side of the POAH suppressed shivering equally on both sides of the body. In unilaterally transected rats, POAH warming on the transected side did not affect shivering, but warming the intact side suppressed shivering equally on both sides of the body. When a unilateral transection of only the lateral part of the hypothalamus included the medial forebrain bundle, the effect was the same as that of a unilateral transection of the whole hypothalamus. These results indicate that no information controlling shivering is exchanged between the left and right POAH and that efferent signals from the POAH, descending through the medial forebrain bundle, cross the midline somewhere below the hypothalamus to innervate both sides of the body equally.

本文言語English
ページ(範囲)R275-R282
ジャーナルAmerican Journal of Physiology - Regulatory Integrative and Comparative Physiology
267
1 36-1
DOI
出版ステータスPublished - 1994
外部発表はい

ASJC Scopus subject areas

  • 生理学
  • 生理学(医学)

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