Hypothalamic region facilitating shivering in rats

Mutsumi Tanaka, Mio Tonouchi, Takayoshi Hosono, Kei Nagashima, Motoko Yanase-Fujiwara, Kazuyuki Kanosue

研究成果: Article

30 引用 (Scopus)

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Although the posterior part of the hypothalamus has long been considered important for thermoregulatory shivering, it is unknown whether the neurons there or the passing fibers are implicated in the response. Exposure of urethane-anesthetized rats to cold (15-21°C) elicits shivering. An injection of muscimol (0.5mM), a GABAA receptor agonist, into the medial part of the hypothalamus, including the dorsomedial and posterior nuclei, suppressed the cold-induced shivering. This result suggests that neurons having an excitatory effect on shivering are in this region of the hypothalamus.

元の言語English
ページ(範囲)625-629
ページ数5
ジャーナルJapanese Journal of Physiology
51
発行部数5
DOI
出版物ステータスPublished - 2001 12 1
外部発表Yes

ASJC Scopus subject areas

  • Physiology

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