Image-based computational hemodynamics of distal aortic arch recoarctation following the Norwood procedure

J. L. Liu, K. Itatani, R. Shiurba, T. Miyakoshi, Y. Qian, A. Murakami, K. Miyaji, M. Umezu

研究成果: Conference contribution

8 被引用数 (Scopus)

抄録

Currently, few applications of computational hemodynamics predict outcomes after palliative surgery for congenital heart defects such as hypolastic left heart syndrome in infants. Here, we report on three-dimensional imaging methods for modeling recoarctation that commonly occurs in the distal aortic arch following the Norwood procedure. We used computer-aided design to simulate seven stages of increasing stenosis, analyze the resulting hemodynamics, and visualize the impairment of blood flow. A disproportionate drop in pressure occurred when stenosis reached 20% of the cross-sectional area of the descending aorta. The corresponding decrease in blood flow in the descending aorta was relatively small, however. Accordingly our findings suggest a reasonable approach to this phenomenon is watchful waiting rather than immediate surgical intervention. Such patient-specific predictions appear to be valuable for minimizing the risks of corrective surgery. These methods also may be applied to procedures for alleviating other congenital heart defects.

本文言語English
ホスト出版物のタイトルProceedings - 2011 4th International Conference on Biomedical Engineering and Informatics, BMEI 2011
ページ318-323
ページ数6
DOI
出版ステータスPublished - 2011 12 1
イベント2011 4th International Conference on Biomedical Engineering and Informatics, BMEI 2011 - Shanghai, China
継続期間: 2011 10 152011 10 17

出版物シリーズ

名前Proceedings - 2011 4th International Conference on Biomedical Engineering and Informatics, BMEI 2011
1

Conference

Conference2011 4th International Conference on Biomedical Engineering and Informatics, BMEI 2011
CountryChina
CityShanghai
Period11/10/1511/10/17

ASJC Scopus subject areas

  • Biomedical Engineering
  • Health Informatics
  • Health Information Management

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