Image-based computational hemodynamics of distal aortic arch recoarctation following the Norwood procedure

J. L. Liu, K. Itatani, R. Shiurba, T. Miyakoshi, Y. Qian, A. Murakami, K. Miyaji, Mitsuo Umezu

    研究成果: Conference contribution

    7 引用 (Scopus)

    抄録

    Currently, few applications of computational hemodynamics predict outcomes after palliative surgery for congenital heart defects such as hypolastic left heart syndrome in infants. Here, we report on three-dimensional imaging methods for modeling recoarctation that commonly occurs in the distal aortic arch following the Norwood procedure. We used computer-aided design to simulate seven stages of increasing stenosis, analyze the resulting hemodynamics, and visualize the impairment of blood flow. A disproportionate drop in pressure occurred when stenosis reached 20% of the cross-sectional area of the descending aorta. The corresponding decrease in blood flow in the descending aorta was relatively small, however. Accordingly our findings suggest a reasonable approach to this phenomenon is watchful waiting rather than immediate surgical intervention. Such patient-specific predictions appear to be valuable for minimizing the risks of corrective surgery. These methods also may be applied to procedures for alleviating other congenital heart defects.

    元の言語English
    ホスト出版物のタイトルProceedings - 2011 4th International Conference on Biomedical Engineering and Informatics, BMEI 2011
    ページ318-323
    ページ数6
    1
    DOI
    出版物ステータスPublished - 2011
    イベント2011 4th International Conference on Biomedical Engineering and Informatics, BMEI 2011 - Shanghai
    継続期間: 2011 10 152011 10 17

    Other

    Other2011 4th International Conference on Biomedical Engineering and Informatics, BMEI 2011
    Shanghai
    期間11/10/1511/10/17

    Fingerprint

    Norwood Procedures
    Hemodynamics
    Arches
    Thoracic Aorta
    Congenital Heart Defects
    Surgery
    Pathologic Constriction
    Blood
    Watchful Waiting
    Computer-Aided Design
    Defects
    Three-Dimensional Imaging
    Palliative Care
    Computer aided design
    Imaging techniques
    Pressure

    ASJC Scopus subject areas

    • Biomedical Engineering
    • Health Informatics
    • Health Information Management

    これを引用

    Liu, J. L., Itatani, K., Shiurba, R., Miyakoshi, T., Qian, Y., Murakami, A., ... Umezu, M. (2011). Image-based computational hemodynamics of distal aortic arch recoarctation following the Norwood procedure. : Proceedings - 2011 4th International Conference on Biomedical Engineering and Informatics, BMEI 2011 (巻 1, pp. 318-323). [6098269] https://doi.org/10.1109/BMEI.2011.6098269

    Image-based computational hemodynamics of distal aortic arch recoarctation following the Norwood procedure. / Liu, J. L.; Itatani, K.; Shiurba, R.; Miyakoshi, T.; Qian, Y.; Murakami, A.; Miyaji, K.; Umezu, Mitsuo.

    Proceedings - 2011 4th International Conference on Biomedical Engineering and Informatics, BMEI 2011. 巻 1 2011. p. 318-323 6098269.

    研究成果: Conference contribution

    Liu, JL, Itatani, K, Shiurba, R, Miyakoshi, T, Qian, Y, Murakami, A, Miyaji, K & Umezu, M 2011, Image-based computational hemodynamics of distal aortic arch recoarctation following the Norwood procedure. : Proceedings - 2011 4th International Conference on Biomedical Engineering and Informatics, BMEI 2011. 巻. 1, 6098269, pp. 318-323, 2011 4th International Conference on Biomedical Engineering and Informatics, BMEI 2011, Shanghai, 11/10/15. https://doi.org/10.1109/BMEI.2011.6098269
    Liu JL, Itatani K, Shiurba R, Miyakoshi T, Qian Y, Murakami A その他. Image-based computational hemodynamics of distal aortic arch recoarctation following the Norwood procedure. : Proceedings - 2011 4th International Conference on Biomedical Engineering and Informatics, BMEI 2011. 巻 1. 2011. p. 318-323. 6098269 https://doi.org/10.1109/BMEI.2011.6098269
    Liu, J. L. ; Itatani, K. ; Shiurba, R. ; Miyakoshi, T. ; Qian, Y. ; Murakami, A. ; Miyaji, K. ; Umezu, Mitsuo. / Image-based computational hemodynamics of distal aortic arch recoarctation following the Norwood procedure. Proceedings - 2011 4th International Conference on Biomedical Engineering and Informatics, BMEI 2011. 巻 1 2011. pp. 318-323
    @inproceedings{05e1788ff3f745c39236a5857807d532,
    title = "Image-based computational hemodynamics of distal aortic arch recoarctation following the Norwood procedure",
    abstract = "Currently, few applications of computational hemodynamics predict outcomes after palliative surgery for congenital heart defects such as hypolastic left heart syndrome in infants. Here, we report on three-dimensional imaging methods for modeling recoarctation that commonly occurs in the distal aortic arch following the Norwood procedure. We used computer-aided design to simulate seven stages of increasing stenosis, analyze the resulting hemodynamics, and visualize the impairment of blood flow. A disproportionate drop in pressure occurred when stenosis reached 20{\%} of the cross-sectional area of the descending aorta. The corresponding decrease in blood flow in the descending aorta was relatively small, however. Accordingly our findings suggest a reasonable approach to this phenomenon is watchful waiting rather than immediate surgical intervention. Such patient-specific predictions appear to be valuable for minimizing the risks of corrective surgery. These methods also may be applied to procedures for alleviating other congenital heart defects.",
    keywords = "computational fluid dynamics, computer-aided design, hemodynamics, medical imaging, Norwood procedure, recoarctation",
    author = "Liu, {J. L.} and K. Itatani and R. Shiurba and T. Miyakoshi and Y. Qian and A. Murakami and K. Miyaji and Mitsuo Umezu",
    year = "2011",
    doi = "10.1109/BMEI.2011.6098269",
    language = "English",
    isbn = "9781424493524",
    volume = "1",
    pages = "318--323",
    booktitle = "Proceedings - 2011 4th International Conference on Biomedical Engineering and Informatics, BMEI 2011",

    }

    TY - GEN

    T1 - Image-based computational hemodynamics of distal aortic arch recoarctation following the Norwood procedure

    AU - Liu, J. L.

    AU - Itatani, K.

    AU - Shiurba, R.

    AU - Miyakoshi, T.

    AU - Qian, Y.

    AU - Murakami, A.

    AU - Miyaji, K.

    AU - Umezu, Mitsuo

    PY - 2011

    Y1 - 2011

    N2 - Currently, few applications of computational hemodynamics predict outcomes after palliative surgery for congenital heart defects such as hypolastic left heart syndrome in infants. Here, we report on three-dimensional imaging methods for modeling recoarctation that commonly occurs in the distal aortic arch following the Norwood procedure. We used computer-aided design to simulate seven stages of increasing stenosis, analyze the resulting hemodynamics, and visualize the impairment of blood flow. A disproportionate drop in pressure occurred when stenosis reached 20% of the cross-sectional area of the descending aorta. The corresponding decrease in blood flow in the descending aorta was relatively small, however. Accordingly our findings suggest a reasonable approach to this phenomenon is watchful waiting rather than immediate surgical intervention. Such patient-specific predictions appear to be valuable for minimizing the risks of corrective surgery. These methods also may be applied to procedures for alleviating other congenital heart defects.

    AB - Currently, few applications of computational hemodynamics predict outcomes after palliative surgery for congenital heart defects such as hypolastic left heart syndrome in infants. Here, we report on three-dimensional imaging methods for modeling recoarctation that commonly occurs in the distal aortic arch following the Norwood procedure. We used computer-aided design to simulate seven stages of increasing stenosis, analyze the resulting hemodynamics, and visualize the impairment of blood flow. A disproportionate drop in pressure occurred when stenosis reached 20% of the cross-sectional area of the descending aorta. The corresponding decrease in blood flow in the descending aorta was relatively small, however. Accordingly our findings suggest a reasonable approach to this phenomenon is watchful waiting rather than immediate surgical intervention. Such patient-specific predictions appear to be valuable for minimizing the risks of corrective surgery. These methods also may be applied to procedures for alleviating other congenital heart defects.

    KW - computational fluid dynamics

    KW - computer-aided design

    KW - hemodynamics

    KW - medical imaging

    KW - Norwood procedure

    KW - recoarctation

    UR - http://www.scopus.com/inward/record.url?scp=84862944402&partnerID=8YFLogxK

    UR - http://www.scopus.com/inward/citedby.url?scp=84862944402&partnerID=8YFLogxK

    U2 - 10.1109/BMEI.2011.6098269

    DO - 10.1109/BMEI.2011.6098269

    M3 - Conference contribution

    AN - SCOPUS:84862944402

    SN - 9781424493524

    VL - 1

    SP - 318

    EP - 323

    BT - Proceedings - 2011 4th International Conference on Biomedical Engineering and Informatics, BMEI 2011

    ER -