In vitro laser Doppler anemometry of pulsatile flow velocity and shear stress measurements downstream from a jellyfish valve in the mitral position of a ventricular assist device

Yos Morsi*, Masahisa Kogure, Mitsuo Umezu

*この研究の対応する著者

研究成果: Article査読

6 被引用数 (Scopus)

抄録

Thrombus formation and hemolysis have both been linked to the dynamic flow characteristics of heart valve prostheses. To enhance our understanding of the flow characteristics past the mitral position of a jellyfish (JF) valve in the left ventricle under physiological pulsatile flow conditions, in vitro laser Doppler anemometry (LDA) measurements were carried out. The hydrodynamic performance of the JF valve was compared with that of a Bjork-Shiley tilting-disk valve (BS mono). The results indicated that both valves created disturbed flow fields and turbulence shear stress levels in the immediate vicinity and up to 1D (diameter of the valvering) downstream from the valve that were capable of causing lethal damage to blood elements. At a location further downstream, the JF valve showed better hydrodynamic performance than the BS in terms of back flow properties and velocity and turbulence stress characteristics. However, any imperfection in the manufacturing of the valve structure, particularly membrane thickness, adversely affected the performance of the JF valve.

本文言語English
ページ(範囲)62-73
ページ数12
ジャーナルJournal of Artificial Organs
2
1
DOI
出版ステータスPublished - 1999 12月 1

ASJC Scopus subject areas

  • 医学(その他)
  • 生体材料
  • 生体医工学
  • 循環器および心血管医学

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