In vitro laser Doppler anemometry of pulsatile flow velocity and shear stress measurements downstream from a jellyfish valve in the mitral position of a ventricular assist device

Yos Morsi, Masahisa Kogure, Mitsuo Umezu

研究成果: Article

5 引用 (Scopus)

抜粋

Thrombus formation and hemolysis have both been linked to the dynamic flow characteristics of heart valve prostheses. To enhance our understanding of the flow characteristics past the mitral position of a jellyfish (JF) valve in the left ventricle under physiological pulsatile flow conditions, in vitro laser Doppler anemometry (LDA) measurements were carried out. The hydrodynamic performance of the JF valve was compared with that of a Bjork-Shiley tilting-disk valve (BS mono). The results indicated that both valves created disturbed flow fields and turbulence shear stress levels in the immediate vicinity and up to 1D (diameter of the valvering) downstream from the valve that were capable of causing lethal damage to blood elements. At a location further downstream, the JF valve showed better hydrodynamic performance than the BS in terms of back flow properties and velocity and turbulence stress characteristics. However, any imperfection in the manufacturing of the valve structure, particularly membrane thickness, adversely affected the performance of the JF valve.

元の言語English
ページ(範囲)62-73
ページ数12
ジャーナルJournal of Artificial Organs
2
発行部数1
DOI
出版物ステータスPublished - 1999 12 1

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Biomaterials
  • Biomedical Engineering
  • Cardiology and Cardiovascular Medicine

フィンガープリント In vitro laser Doppler anemometry of pulsatile flow velocity and shear stress measurements downstream from a jellyfish valve in the mitral position of a ventricular assist device' の研究トピックを掘り下げます。これらはともに一意のフィンガープリントを構成します。

  • これを引用