This study summarizes our three-year experiences in implantation of assist device made of SPU (segmented polyurethanes) in goats, emphasizing the long-term blood/material interactions. The methods employed in this study are subdivided into three methodologies: (1) Macroscopic and microscopic observations of thrombus on surfaces, (2) Detection of infarctions at the downstreamed blood-circulating organs due to (micro)embolization and (3) Monitoring of changes in hematological parameters of circulating blood components, which include the levels and physiological functionalities. Especially, the third one will give the information on the dynamic (or time-variant) state of blood/material interactions. This will deepen the understanding of in vivo complicated blood/material interactions.
|出版ステータス||Published - 1984 12 1|
ASJC Scopus subject areas
- Materials Science(all)