In Vivo Gold Complex Catalysis within Live Mice

Kazuki Tsubokura, Kenward K H Vong, Ambara R. Pradipta, Akihiro Ogura, Sayaka Urano, Tsuyoshi Tahara, Satoshi Nozaki, Hirotaka Onoe, Youichi Nakao, Regina Sibgatullina, Almira Kurbangalieva, Yasuyoshi Watanabe, Katsunori Tanaka

    研究成果: Article

    34 引用 (Scopus)

    抄録

    Metal complex catalysis within biological systems is largely limited to cell and bacterial systems. In this work, a glycoalbumin–AuIII complex was designed and developed that enables organ-specific, localized propargyl ester amidation with nearby proteins within live mice. The targeted reactivity can be imaged through the use of Cy7.5- and TAMRA-linked propargyl ester based fluorescent probes. This targeting system could enable the exploitation of other metal catalysis strategies for biomedical and clinical applications.

    元の言語English
    ページ(範囲)3579-3584
    ページ数6
    ジャーナルAngewandte Chemie - International Edition
    56
    発行部数13
    DOI
    出版物ステータスPublished - 2017 3 20

    Fingerprint

    Gold
    Catalysis
    Esters
    Coordination Complexes
    Biological systems
    Metal complexes
    Fluorescent Dyes
    Metals
    Proteins

    ASJC Scopus subject areas

    • Catalysis
    • Chemistry(all)

    これを引用

    Tsubokura, K., Vong, K. K. H., Pradipta, A. R., Ogura, A., Urano, S., Tahara, T., ... Tanaka, K. (2017). In Vivo Gold Complex Catalysis within Live Mice. Angewandte Chemie - International Edition, 56(13), 3579-3584. https://doi.org/10.1002/anie.201610273

    In Vivo Gold Complex Catalysis within Live Mice. / Tsubokura, Kazuki; Vong, Kenward K H; Pradipta, Ambara R.; Ogura, Akihiro; Urano, Sayaka; Tahara, Tsuyoshi; Nozaki, Satoshi; Onoe, Hirotaka; Nakao, Youichi; Sibgatullina, Regina; Kurbangalieva, Almira; Watanabe, Yasuyoshi; Tanaka, Katsunori.

    :: Angewandte Chemie - International Edition, 巻 56, 番号 13, 20.03.2017, p. 3579-3584.

    研究成果: Article

    Tsubokura, K, Vong, KKH, Pradipta, AR, Ogura, A, Urano, S, Tahara, T, Nozaki, S, Onoe, H, Nakao, Y, Sibgatullina, R, Kurbangalieva, A, Watanabe, Y & Tanaka, K 2017, 'In Vivo Gold Complex Catalysis within Live Mice', Angewandte Chemie - International Edition, 巻. 56, 番号 13, pp. 3579-3584. https://doi.org/10.1002/anie.201610273
    Tsubokura K, Vong KKH, Pradipta AR, Ogura A, Urano S, Tahara T その他. In Vivo Gold Complex Catalysis within Live Mice. Angewandte Chemie - International Edition. 2017 3 20;56(13):3579-3584. https://doi.org/10.1002/anie.201610273
    Tsubokura, Kazuki ; Vong, Kenward K H ; Pradipta, Ambara R. ; Ogura, Akihiro ; Urano, Sayaka ; Tahara, Tsuyoshi ; Nozaki, Satoshi ; Onoe, Hirotaka ; Nakao, Youichi ; Sibgatullina, Regina ; Kurbangalieva, Almira ; Watanabe, Yasuyoshi ; Tanaka, Katsunori. / In Vivo Gold Complex Catalysis within Live Mice. :: Angewandte Chemie - International Edition. 2017 ; 巻 56, 番号 13. pp. 3579-3584.
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    AU - Urano, Sayaka

    AU - Tahara, Tsuyoshi

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