Influence of wall thickness on fluid-structure interaction computations of cerebral aneurysms

Ryo Torii, Marie Oshima, Toshio Kobayashi, Kiyoshi Takagi, Tayfun E. Tezduyar

研究成果: Article

77 引用 (Scopus)

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Fluid-structure interaction (FSI) analyses of cerebral aneurysm using patient-specific geometry with uniform and pathological aneurysmal wall thickness models are carried out. The objective is to assess the influence of the wall thickness on the FSI and hemodynamics in aneurysms. Two aneurysm models that were reconstructured based on CT images are used. The arterial wall thickness is set to 0.3mm for the non-aneurysmal artery and to 0.05mm for the aneurysmal wall based on experimental findings. Another set of aneurysm models with a uniform wall thickness of 0.3mm for the entire model is used for comparison. The FSI simulations are carried out using the deforming-spatial-domain/stabilized space-time method with physiological inflow and pressure profiles. Computations with different aneurysmal wall thicknesses depict considerable differences in displacement, flow velocity and wall shear stress (WSS). The wall displacement for the pathological wall model is 61% larger than that of the uniform wall model. Consequently, the flow velocities in the aneurysm with the pathological wall model are lower, and that results in a 51% reduction in WSS on the aneurismal wall. Because low WSS on the aneurymal wall is linked to growth and rupture risk of aneurysm, the results suggest that using uniform wall thickness for the aneurysmal wall could underestimate risk in aneurysms.

元の言語English
ページ(範囲)336-347
ページ数12
ジャーナルInternational Journal for Numerical Methods in Biomedical Engineering
26
発行部数3-4
DOI
出版物ステータスPublished - 2010 3 1
外部発表Yes

ASJC Scopus subject areas

  • Software
  • Biomedical Engineering
  • Modelling and Simulation
  • Molecular Biology
  • Computational Theory and Mathematics
  • Applied Mathematics

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