Inhibition by beta-carotene - rich algae Dunaliella of spontaneous mammary tumourigenesis in mice

H. Nagasawa, R. Konishi, N. Sensui, K. Yamamoto, A. Ben-Amotz

研究成果: Article査読

19 被引用数 (Scopus)

抄録

Effects of beta-carotene - rich algae Dunaliella on spontaneous mammary tumourigenesis were studied in SHN mice. In both breeder and virgin mice, mammary tumourigenesis was significantly inhibited in the experimental groups fed diets supplemented with spray dried powder of D. bardawil and oily solution of D. salina Teod. extract compared with the control. There was little difference between the experimental and the control groups in plasma prolactin level, endocrine organ weights and pattern of oestrous cycles. Moreover, mammary gland susceptibility to mammotrophic hormones was affected little by Dunaliella. These results suggest that the inhibition by Dunaliella of spontaneous mammary tumourigenesis of mice may not be through their modulation of endocrine systems.

本文言語English
ページ(範囲)71-76
ページ数6
ジャーナルAnticancer Research
9
1
出版ステータスPublished - 1989
外部発表はい

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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