@article{72ac6c92d5ed436eaa373e136d21c010,
title = "Inkjet-Printed Neural Electrodes with Mechanically Gradient Structure",
abstract = "Flexible materials are important for the development of neural probes in recording stable signals (spikes) in vivo. Here, we present inkjet-printed, flexible neural probes for spike recording by using polymeric thin films. The neural probes were constructed from 400 nm-thick poly(d,l-lactic acid) nanofilms, inkjet-printed lines consisting of Au and poly(3,4-ethylenedioxythiophene):polystyrenesulfonate nanoinks, and fluoropolymer layers. Microelectrodes were exposed by cutting the edge with a razor. The 6 μm-thick probes were connected to the external amplifiers by gradual increase of stiffness with thickness-dependent manner. The probe was formed into a needle shape, which recorded spikes from mouse thalamus in vivo.",
keywords = "inkjet printing, neural electrode, optogenetics, polymer nanofilm, printed electronics",
author = "Nana Kokubo and Masashi Arake and Kento Yamagishi and Yuji Morimoto and Shinji Takeoka and Hiroyuki Ohta and Toshinori Fujie",
note = "Funding Information: This work was supported by the Precursory Research for Embryonic Science and Technology (PRESTO) program from the Japan Science and Technology Agency (JST; Grant No. JPMJPR152A), JSPS KAKENHI (Grant Nos. 16K08923, 17K20116, 18H03539, 18H05469), a Grant-in-Aid for JSPS Fellows (Grant No. 16J07140), JSPS Core-to-Core Program, the Noguchi Institute, and the Tanaka Memorial Foundation. Publisher Copyright: Copyright {\textcopyright} 2018 American Chemical Society.",
year = "2019",
month = jan,
day = "22",
doi = "10.1021/acsabm.8b00574",
language = "English",
volume = "2",
pages = "20--26",
journal = "ACS Applied Bio Materials",
issn = "2576-6422",
publisher = "American Chemical Society",
number = "1",
}