Inkjet-Printed Neural Electrodes with Mechanically Gradient Structure

Nana Kokubo, Masashi Arake, Kento Yamagishi, Yuji Morimoto, Shinji Takeoka, Hiroyuki Ohta*, Toshinori Fujie

*この研究の対応する著者

研究成果: Article査読

8 被引用数 (Scopus)

抄録

Flexible materials are important for the development of neural probes in recording stable signals (spikes) in vivo. Here, we present inkjet-printed, flexible neural probes for spike recording by using polymeric thin films. The neural probes were constructed from 400 nm-thick poly(d,l-lactic acid) nanofilms, inkjet-printed lines consisting of Au and poly(3,4-ethylenedioxythiophene):polystyrenesulfonate nanoinks, and fluoropolymer layers. Microelectrodes were exposed by cutting the edge with a razor. The 6 μm-thick probes were connected to the external amplifiers by gradual increase of stiffness with thickness-dependent manner. The probe was formed into a needle shape, which recorded spikes from mouse thalamus in vivo.

本文言語English
ページ(範囲)20-26
ページ数7
ジャーナルACS Applied Bio Materials
2
1
DOI
出版ステータスPublished - 2019 1月 22

ASJC Scopus subject areas

  • 生体材料
  • 化学 (全般)
  • 生体医工学
  • 生化学、医学

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