This paper describes a sound source separation method for polyphonic sound mixtures o music to build an instrument equalizer for remixing multiple tracks separated from compact-disc recordings by changing the volume level of each track. Although such, mixtures usually include both harmonic and inharmonic sounds, the difficulties in dealing with both types of sounds together have not been addressed in most previous methods that have focused on either of the two types separately. We therefore developed an integrated weighted-mixture model consisting of both harmonic-structure and inharmonic-structure tone models (generative models for the power spectrogram). On the basis of the MAP estimation using the EM algorithm, we estimated all model parameters of this, integrated model under several original constraints for preventing over-training and maintaining intra-instrument consistency. Using standard MIDI files as prior information of the model parameters, We applied this model to compact-disc recordings and achieved the instrument equalizer.