Interleukin-1 increases norepinephrine turnover in the spleen and lung in rats

Megumi Akiyoshi, Yasutake Shimizu, Masayuki Saito

研究成果: Article

55 引用 (Scopus)

抜粋

To clarify effects of interleukin-1 on sympathetic nerve activity, norepinephrine turnover in various organs was assessed in rats after intraperitoneal injection of recombinant human interleukin-1β. Interleukin-1 administration increased norepinephrine turnover in the spleen, lung and hypothalamus without appreciable effect in the heart, liver, submandibular gland, thymus, pancreas, brown adipose tissue and medulla oblongata. Similar changes in norepinephrine turnover were also found after the administration of bacterial endotoxin. It was concluded that interleukin-1 activates the sympathetic nerves specifically in the spleen and lung.

元の言語English
ページ(範囲)1266-1270
ページ数5
ジャーナルBiochemical and Biophysical Research Communications
173
発行部数3
DOI
出版物ステータスPublished - 1990 12 31
外部発表Yes

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Molecular Biology

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