Intracellular click reaction with a fluorescent chemical Ca2+ indicator to prolong its cytosolic retention

Yoshiaki Takei, Atsushi Murata, Kento Yamagishi, Satoshi Arai, Hideki Nakamura, Takafumi Inoue, Shinji Takeoka

研究成果: Article査読

6 被引用数 (Scopus)

抄録

The powerful strategy of “intracellular click reaction” was used to retain a chemical Ca2+ indicator in the cytosol. Specifically, a novel clickable Ca2+ indicator “N3-fura-2 AM” was coupled with dibenzylcyclooctyl-modified biomacromolecules via copper-free click reaction in living cells and Ca2+ oscillation was observed for an extended period of time.

本文言語English
ページ(範囲)7313-7315
ページ数3
ジャーナルChemical Communications
49
66
DOI
出版ステータスPublished - 2013 7 23

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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