抄録
Bioelectrical impedance spectroscopy (BIS) can assess intracellular water (ICW) and total water (TW) in limbs. This study aimed to examine whether BIS can explain a part of the inter-individual variation of the muscle size-strength relationship in older adults. We analyzed the data of 79 participants aged 64–86 years. The maximal voluntary isometric torques of dorsiflexion and plantar flexion on the right side were measured. The anterior and posterior muscle thickness (MT) in the right lower leg was assessed using ultrasonography. The length of the right lower leg (L) was measured, and the ICW-to-TW ratio (ICW/TW) in the right lower leg was obtained using BIS. The MT was multiplied by L to represent an index of muscle volume (MV). Correlation and stepwise regression analyses were performed. The anterior and posterior MT × L significantly and positively correlated with the muscle torque of dorsiflexion and plantar flexion (r = 0.710 and 0.649, respectively, P < 0.001). In the stepwise regression analyses, ICW/TW was selected as a significant predictor of muscle torque independent of MT × L (P < 0.05) for both dorsiflexion and plantar flexion. Electrical parameters of BIS (membrane capacitance, characteristics frequency, and phase angle) in the lower leg also significantly correlated with muscle torques. In addition, the skeletal muscle mass index (appendicular lean mass/height2) was also associated with ICW/TW (P < 0.001). The present results suggest that ICW/TW explains the interindividual variations of the muscle size-strength relationship.
| 元の言語 | English |
|---|---|
| ページ（範囲） | 120-127 |
| ページ数 | 8 |
| ジャーナル | Experimental Gerontology |
| 巻 | 113 |
| DOI | |
| 出版物ステータス | Published - 2018 11 1 |
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ASJC Scopus subject areas
- Biochemistry
- Ageing
- Molecular Biology
- Genetics
- Endocrinology
- Cell Biology
これを引用
Intracellular-to-total water ratio explains the variability of muscle strength dependence on the size of the lower leg in the elderly. / Yoshida, Tsukasa; Yamada, Yosuke; Tanaka, Fumiko; Yamagishi, Takaki; Shibata, Shigenobu; Kawakami, Yasuo.
：: Experimental Gerontology, 巻 113, 01.11.2018, p. 120-127.研究成果: Article
}
TY - JOUR
T1 - Intracellular-to-total water ratio explains the variability of muscle strength dependence on the size of the lower leg in the elderly
AU - Yoshida, Tsukasa
AU - Yamada, Yosuke
AU - Tanaka, Fumiko
AU - Yamagishi, Takaki
AU - Shibata, Shigenobu
AU - Kawakami, Yasuo
PY - 2018/11/1
Y1 - 2018/11/1
N2 - Bioelectrical impedance spectroscopy (BIS) can assess intracellular water (ICW) and total water (TW) in limbs. This study aimed to examine whether BIS can explain a part of the inter-individual variation of the muscle size-strength relationship in older adults. We analyzed the data of 79 participants aged 64–86 years. The maximal voluntary isometric torques of dorsiflexion and plantar flexion on the right side were measured. The anterior and posterior muscle thickness (MT) in the right lower leg was assessed using ultrasonography. The length of the right lower leg (L) was measured, and the ICW-to-TW ratio (ICW/TW) in the right lower leg was obtained using BIS. The MT was multiplied by L to represent an index of muscle volume (MV). Correlation and stepwise regression analyses were performed. The anterior and posterior MT × L significantly and positively correlated with the muscle torque of dorsiflexion and plantar flexion (r = 0.710 and 0.649, respectively, P < 0.001). In the stepwise regression analyses, ICW/TW was selected as a significant predictor of muscle torque independent of MT × L (P < 0.05) for both dorsiflexion and plantar flexion. Electrical parameters of BIS (membrane capacitance, characteristics frequency, and phase angle) in the lower leg also significantly correlated with muscle torques. In addition, the skeletal muscle mass index (appendicular lean mass/height2) was also associated with ICW/TW (P < 0.001). The present results suggest that ICW/TW explains the interindividual variations of the muscle size-strength relationship.
AB - Bioelectrical impedance spectroscopy (BIS) can assess intracellular water (ICW) and total water (TW) in limbs. This study aimed to examine whether BIS can explain a part of the inter-individual variation of the muscle size-strength relationship in older adults. We analyzed the data of 79 participants aged 64–86 years. The maximal voluntary isometric torques of dorsiflexion and plantar flexion on the right side were measured. The anterior and posterior muscle thickness (MT) in the right lower leg was assessed using ultrasonography. The length of the right lower leg (L) was measured, and the ICW-to-TW ratio (ICW/TW) in the right lower leg was obtained using BIS. The MT was multiplied by L to represent an index of muscle volume (MV). Correlation and stepwise regression analyses were performed. The anterior and posterior MT × L significantly and positively correlated with the muscle torque of dorsiflexion and plantar flexion (r = 0.710 and 0.649, respectively, P < 0.001). In the stepwise regression analyses, ICW/TW was selected as a significant predictor of muscle torque independent of MT × L (P < 0.05) for both dorsiflexion and plantar flexion. Electrical parameters of BIS (membrane capacitance, characteristics frequency, and phase angle) in the lower leg also significantly correlated with muscle torques. In addition, the skeletal muscle mass index (appendicular lean mass/height2) was also associated with ICW/TW (P < 0.001). The present results suggest that ICW/TW explains the interindividual variations of the muscle size-strength relationship.
KW - Heterogeneity
KW - Muscle composition
KW - Muscle quality
KW - Sarcopenia
KW - Skeletal muscle tissue
KW - Specific torque
KW - Water fraction
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U2 - 10.1016/j.exger.2018.09.022
DO - 10.1016/j.exger.2018.09.022
M3 - Article
C2 - 30267871
AN - SCOPUS:85054437656
VL - 113
SP - 120
EP - 127
JO - Experimental Gerontology
JF - Experimental Gerontology
SN - 0531-5565
ER -