Investigation of a hydrodynamic performance of a ventricular assist device after its long-term use in clinical application

Yuma Kokuzawa*, Tomohiro Shima, Masateru Furusato, Kazuhiko Ito, Takashi Tanaka, Toshihiro Igarashi, Tomohiro Nishinaka, Kiyotaka Iwasaki, Mitsuo Umezu

*この研究の対応する著者

研究成果: Conference contribution

抄録

A long-term durability of a ventricular assist device (VAD) is required due to a shortage of donor hearts for cardiac transplantation, but there is no analyzed pump data after long-term use. This study aimed to perform a comparative study between new VAD and VADs after long-term use. The hydrodynamic performance of the used Toyobo VADs (mean period of 5 months with the maximum of 12 months) was evaluated in a mock circulatory system, where a new VAD was used as a control. Although a remarkable difference was not observed in terms of mean flow rate, flow and pressure waveforms varied significantly. Then, the pressure-volume relationship of each pump was measured. It was found that the capacity of long-term VADs was reduced. Although a further study is required, these results suggested that a long-term use of VAD may cause a change in mechanical properties of polymer materials.

本文言語English
ホスト出版物のタイトルLife System Modeling and Simulation - International Conference, LSMS 2007, Proceedings
出版社Springer Verlag
ページ429-435
ページ数7
ISBN(印刷版)9783540747703
DOI
出版ステータスPublished - 2007
イベント2007 International Conference on Life System Modeling and Simulation, LSMS 2007 - Shanghai, China
継続期間: 2007 9 142007 9 17

出版物シリーズ

名前Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
4689 LNBI
ISSN(印刷版)0302-9743
ISSN(電子版)1611-3349

Conference

Conference2007 International Conference on Life System Modeling and Simulation, LSMS 2007
国/地域China
CityShanghai
Period07/9/1407/9/17

ASJC Scopus subject areas

  • 理論的コンピュータサイエンス
  • コンピュータ サイエンス(全般)

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