抄録
Disulfide bonds of peptides were effectively established between S-protected cysteine residues as well as free cysteine residues by the action of dimethylsulfoxide in trifluoroacetic acid. Oxytocin and a-human calcitonin gene-related peptide were synthesized using this oxidation system. The feasibility of this method for the formation of two disulfide bridges of apamin was also examined.
本文言語 | English |
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ページ(範囲) | 1030-1034 |
ページ数 | 5 |
ジャーナル | Chemical and Pharmaceutical Bulletin |
巻 | 41 |
号 | 6 |
DOI | |
出版ステータス | Published - 1993 |
外部発表 | はい |
ASJC Scopus subject areas
- 化学 (全般)
- 創薬