Involvement of the suprachiasmatic nucleus in body temperature modulation by food deprivation in rats

Su Liu, Xiao Ming Chen, Tamae Yoda, Kei Nagashima, Yutaka Fukuda, Kazuyuki Kanosue

研究成果: Article

28 引用 (Scopus)

抜粋

Recently we found that food-deprived rats kept under a light-dark cycle showed a progressive reduction in body temperature during the light phase on each subsequent day while body temperature in the dark phase did not differ from baseline values. In this study, we investigated the effect of lesioning the hypothalamic suprachiasmatic nucleus (SCN) on body temperature modulation by food deprivation. In the SCN-lesioned rats in which daily rhythms of body temperature and activity were abolished, body temperature was unchanged by food deprivation. We also examined the effect of food deprivation on the daily changes in Fos expression in the SCN. Under normal fed conditions the number of SCN cells expressing Fos is high during the day and low at night. Food deprivation attenuated the amplitude of this daily change in Fos expression in the SCN. This tendency was prominent in the dorsal part of the SCN, while the ventral part showed no effect of food deprivation. These findings suggest that the SCN plays some role in body temperature modulation due to food deprivation.

元の言語English
ページ(範囲)26-36
ページ数11
ジャーナルBrain Research
929
発行部数1
DOI
出版物ステータスPublished - 2002 3 1
外部発表Yes

ASJC Scopus subject areas

  • Neuroscience(all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

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