Iridium(I)-catalyzed direct C-H bond alkylation of the C-7 position of indolines with alkenes

Shiguang Pan, Naoto Ryu, Takanori Shibata*

*この研究の対応する著者

研究成果: Article査読

82 被引用数 (Scopus)

抄録

A cationic iridium-catalyzed C-7 alkylation of N-substituted indoline derivatives with various alkenes has been developed. A variety of 7-alkylindolines were obtained in moderate to high yields. This protocol relies on the use of the carbonyl group on the nitrogen atom of indoline as a directing group and it is potentially applicable to the large-scale synthesis of 7-alkylindoles.

本文言語English
ページ(範囲)929-933
ページ数5
ジャーナルAdvanced Synthesis and Catalysis
356
5
DOI
出版ステータスPublished - 2014 3月 24

ASJC Scopus subject areas

  • 触媒
  • 有機化学

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