Isolation of 1-methylherbipoline salts of halisulfate-1 and of suvanine as serine protease inhibitors from a marine sponge, Coscinoderma mathewsi

J. Kimura, E. Ishizuka, Y. Nakao, W. Y. Yoshida, P. J. Scheuer, M. Kelly-Borges

研究成果: Article査読

38 被引用数 (Scopus)

抄録

Bioassay-guided isolation of serine protease inhibitors from a marine sponge, Coscinoderma mathewsi, has yielded 1-methylherbipoline salts of halisulfate-1 and of suvanine. Structures of these compounds were identified by spectroscopic analyses and literature data. Antithrombin and antitrypsin activity was determined.

本文言語English
ページ(範囲)248-250
ページ数3
ジャーナルJournal of Natural Products
61
2
DOI
出版ステータスPublished - 1998 1 1
外部発表はい

ASJC Scopus subject areas

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

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