Lack of age-related increase in carotid artery wall viscosity in cardiorespiratory fit men

Hiroshi Kawano, Kenta Yamamoto, Yuko Gando, Michiya Tanimoto, Haruka Murakami, Yumi Ohmori, Kiyoshi Sanada, Izumi Tabata, Mitsuru Higuchi, Motohiko Miyachi

研究成果: Article

6 引用 (Scopus)

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OBJECTIVES:: Age-related arterial stiffening and reduction of arterial elasticity are attenuated in individuals with high levels of cardiorespiratory fitness. Viscosity is another mechanical characteristic of the arterial wall; however, the effects of age and cardiorespiratory fitness have not been determined. We examined the associations among age, cardiorespiratory fitness and carotid arterial wall viscosity. METHODS:: A total of 111 healthy men, aged 25-39 years (young) and 40-64 years (middle-aged), were divided into either cardiorespiratory fit or unfit groups on the basis of peak oxygen uptake. The common carotid artery was measured noninvasively by tonometry and automatic tracking of B-mode images to obtain instantaneous pressure and diameter hysteresis loops, and we calculated the effective compliance, isobaric compliance and viscosity index. RESULTS:: In the middle-aged men, the viscosity index was larger in the unfit group than in the fit group (2533 vs. 2018âmmHg·s/mm, respectively: Pâ Š0.05), but this was not the case in the young men. In addition, effective and isobaric compliance were increased, and viscosity index was increased with advancing age, but these parameters were unaffected by cardiorespiratory fitness level. CONCLUSION:: These results suggest that the wall viscosity in the central artery is increased with advancing age and that the age-associated increase in wall viscosity may be attenuated in cardiorespiratory fit men.

元の言語English
ページ(範囲)2370-2379
ページ数10
ジャーナルJournal of Hypertension
31
発行部数12
DOI
出版物ステータスPublished - 2013 12
外部発表Yes

ASJC Scopus subject areas

  • Internal Medicine
  • Physiology
  • Cardiology and Cardiovascular Medicine

フィンガープリント Lack of age-related increase in carotid artery wall viscosity in cardiorespiratory fit men' の研究トピックを掘り下げます。これらはともに一意のフィンガープリントを構成します。

  • これを引用

    Kawano, H., Yamamoto, K., Gando, Y., Tanimoto, M., Murakami, H., Ohmori, Y., Sanada, K., Tabata, I., Higuchi, M., & Miyachi, M. (2013). Lack of age-related increase in carotid artery wall viscosity in cardiorespiratory fit men. Journal of Hypertension, 31(12), 2370-2379. https://doi.org/10.1097/HJH.0b013e328364cbba