Lifestyle modification decreases arterial stiffness in overweight and obese men: Dietary modification vs. exercise training

Seiji Maeda*, Asako Zempo-Miyaki, Hiroyuki Sasai, Takehiko Tsujimoto, Rina So, Kiyoji Tanaka

*この研究の対応する著者

研究成果: Article査読

18 被引用数 (Scopus)

抄録

Obesity and increased arterial stiffness are independent risk factors for cardiovascular disease. Arterial stiffness is increased in obese individuals than in age-matched nonobese individuals. We demonstrated that dietary modification and exercise training are effective in reducing arterial stiffness in obese persons. However, the differences in the effect on arterial stiffness between dietary modification and exercise training are unknown. The purpose of the current study was to compare the effect of dietary modification and aerobic exercise training on arterial stiffness and endothelial function in overweight and obese persons. Forty-five overweight and obese men (48 ± 1 year) completed either a dietary modification (well-balanced nutrient, 1680 kcal/day) or an exercise-training program (walking, 40-60 min/day, 3 days/week) for 12 weeks. Before and after the intervention, all participants underwent anthropometric measurements. Arterial stiffness was measured based on carotid arterial compliance, brachial-ankle pulse wave velocity (baPWV), and endothelial function was determined by circulating level of endothelin-1 (ET-1) and nitric oxide metabolite (nitrites/nitrate as metabolite: NOx). Body mass and waist circumference significantly decreased after both intervention programs. Weight loss was greater after dietary modification than after exercise training (-10.1 ± 0.6 kg vs. -3.6 ± 0.5 kg, p < .01). Although arterial stiffness and the plasma levels of ET-1 and NOx were improved after dietary modification or exercise training, there were no differences in those improvements between the 2 types of interventions. Exercise training improves arterial function in obese men without as much weight loss as after dietary modification.

本文言語English
ページ(範囲)69-77
ページ数9
ジャーナルInternational journal of sport nutrition and exercise metabolism
25
1
DOI
出版ステータスPublished - 2015 2 1
外部発表はい

ASJC Scopus subject areas

  • 医学(その他)
  • 整形外科およびスポーツ医学
  • 栄養および糖尿病

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