Liposomal heme as oxygen carrier under semi-physiological conditions orientation study of heme embedded in a phospholipid bilayer by an electrooptical method

Eishun Tsuchida, Hiroyuki Nishide, Mikiya Sekine, Akihiko Yamagishi

研究成果: Article

8 引用 (Scopus)

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The meso-tetra(α,α,α,α(o-pivalamidophenyl))porphinato iron-mono(1-lauryl-2-methylimidazole) complex embedded in the bilayer of dimyristoylphosphatidylcholine (liposomal heme) binds molecular oxygen reversibly at pH 7 and 37°C. Orientation of the iron porphyrin complex in the phospholipid bilayer was studied by electric birefringence and dichroism. It was observed that both the phospholipid bibilayer of liposome and the porphyrin plane are oriented nearly in parallel to the electric field. Therefore the angle between the porphyrin plane and the bilayer is considered to be practically small.

元の言語English
ページ(範囲)274-278
ページ数5
ジャーナルBBA - Biomembranes
734
発行部数2
DOI
出版物ステータスPublished - 1983 10 12

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ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Cell Biology

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