Liposomal heme as oxygen carrier under semi-physiological conditions orientation study of heme embedded in a phospholipid bilayer by an electrooptical method

Eishun Tsuchida*, Hiroyuki Nishide, Mikiya Sekine, Akihiko Yamagishi

*この研究の対応する著者

研究成果: Article査読

8 被引用数 (Scopus)

抄録

The meso-tetra(α,α,α,α(o-pivalamidophenyl))porphinato iron-mono(1-lauryl-2-methylimidazole) complex embedded in the bilayer of dimyristoylphosphatidylcholine (liposomal heme) binds molecular oxygen reversibly at pH 7 and 37°C. Orientation of the iron porphyrin complex in the phospholipid bilayer was studied by electric birefringence and dichroism. It was observed that both the phospholipid bibilayer of liposome and the porphyrin plane are oriented nearly in parallel to the electric field. Therefore the angle between the porphyrin plane and the bilayer is considered to be practically small.

本文言語English
ページ(範囲)274-278
ページ数5
ジャーナルBBA - Biomembranes
734
2
DOI
出版ステータスPublished - 1983 10 12

ASJC Scopus subject areas

  • 生化学
  • 生物理学
  • 細胞生物学

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