Live imaging of cell apoptosis using FRET-based bioprobes in MEMS fabricated microculture dish

R. Kajiyama, Y. Edagawa, M. Suzuki, A. Nakahara, D. H. Yoon, T. Sekiguchi, S. Shoji

研究成果: Conference contribution

抄録

We proposed a novel approach for monitoring cellular caspase-3 activities and controlling morphology of a cell under real time condition using fluorescence resonance energy transfer (FRET) based-bioprobes and the MEMS fabricated microculture dish. The FRET-based bioprobes monitoring caspase-3 activities were successfully introduced into the PC12 cells. In addition, the morphology of the bioprobes introduced cell was controlled along the patterned micro grooves. We observed the activation of the protease and the morphology change of the cell simultaneously when the cells were exposed to an apoptosis inducer.

本文言語English
ホスト出版物のタイトル2013 Transducers and Eurosensors XXVII
ホスト出版物のサブタイトルThe 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013
ページ2560-2563
ページ数4
DOI
出版ステータスPublished - 2013 12 1
イベント2013 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013 - Barcelona, Spain
継続期間: 2013 6 162013 6 20

出版物シリーズ

名前2013 Transducers and Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013

Conference

Conference2013 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013
国/地域Spain
CityBarcelona
Period13/6/1613/6/20

ASJC Scopus subject areas

  • ハードウェアとアーキテクチャ
  • 電子工学および電気工学

フィンガープリント

「Live imaging of cell apoptosis using FRET-based bioprobes in MEMS fabricated microculture dish」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル