Logic operation in DNA nano device: Electrical input/output through biological nanopore

Kosuke Inoue, Ryuji Kawano, Hiroki Yasuga, Masahiro Takinoue, Toshihisa Osaki, Koki Kamiya, Norihisa Miki, Shoji Takeuchi

研究成果: Conference contribution

2 被引用数 (Scopus)

抄録

This paper describes DNA logic gates with using biological nanopores integrated in the lipid-coated droplet networks. As the biological nanopore, alpha-hemolysin (αHL) is reconstituted in droplet interface bilayers (DIBs) which can be prepared with splitting and re-attaching the lipid monolayers by mechanical motion in split-and-contact device; SCD. Since DIBs can be instantly formed by SCD, we can use the rupture of DIBs to transfer DNA between droplets as inputs for logic operation. In this study, we demonstrated OR and NOT gates using this input system with SCD. The rapid and repeated calculation can be performed in this system.

本文言語English
ホスト出版物のタイトル17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
出版社Chemical and Biological Microsystems Society
ページ1881-1883
ページ数3
ISBN(印刷版)9781632666246
出版ステータスPublished - 2013 1 1
外部発表はい
イベント17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013 - Freiburg, Germany
継続期間: 2013 10 272013 10 31

出版物シリーズ

名前17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
3

Conference

Conference17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
CountryGermany
CityFreiburg
Period13/10/2713/10/31

ASJC Scopus subject areas

  • Bioengineering

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