Microfluidic analysis of neurodegenerative impact evoked by local stimulation-triggered apoptotic information

Yoshikuni Edagawa*, Taku Watanabe, Masaru Fujii, Kentaro Kawai, Shuichi Shoji

*この研究の対応する著者

研究成果: Conference contribution

1 被引用数 (Scopus)

抄録

Microfluidic analysis system for microscopic pharmacology handling single cells was demonstrated in this paper, which included the stimulation only on a local area of the target cell by using the laminar flowing of drug solutions and the systemic monitoring of the effect evoked on the whole cell. By this system, it was first elucidated that the stimulation of the tip of neurite with an apoptosis-inducing drug resulted in the expression of an apoptotic marker in the cell body as a remote position from the stimulated point. This indicates a new paradigm of microscopic pharmacology opens up here.

本文言語English
ホスト出版物のタイトル15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
ページ1511-1513
ページ数3
出版ステータスPublished - 2011
イベント15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011 - Seattle, WA, United States
継続期間: 2011 10 22011 10 6

出版物シリーズ

名前15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
3

Conference

Conference15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
国/地域United States
CitySeattle, WA
Period11/10/211/10/6

ASJC Scopus subject areas

  • 制御およびシステム工学

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