Modeling of viscoelastic and nonlinear material properties of liver tissue using fractional calculations

Yo Kobayashi*, Atsushi Kato, Hiroki Watanabe, Takeharu Hoshi, Kazuya Kawamura, Masakatsu G. Fujie

*この研究の対応する著者

研究成果: Article査読

22 被引用数 (Scopus)

抄録

We present a material model to represent the viscoelastic and material, nonlinear properties of liver tissue for needle insertion simulation. Material properties of liver tissue were measured using a rheometer and modeled from the measured data. The liver viscoelastic characteristics were represented by differential equations, including the fractional derivative term. Next, nonlinearity with respect to the fractional derivative was measured, and the stress-strain relationship using a cubic function was modeled. The material properties of liver tissue were represented by a simple equation with only a few parameters. We evaluated the variety of each stiffness parameter from measurements of 50 samples. The results showed a high degree of variation in each stiffness parameter, especially with respect to nonlinearity. Moreover, each parameter had a low correlation coefficient. We also modeled the probability of variation in material properties from these results to provide a basis for deformation simulations considering individual patient differences.

本文言語English
ページ(範囲)177-187
ページ数11
ジャーナルJournal of Biomechanical Science and Engineering
7
2
DOI
出版ステータスPublished - 2012

ASJC Scopus subject areas

  • 生体医工学

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