Moderate physical exercise induces the oxidation of human blood protein thiols

Takayo Inayama*, Jun Oka, Misato Kashiba, Makoto Saito, Mitsuru Higuchi, Keizo Umegaki, Yorihiro Yamamoto, Mitsuo Matsuda

*この研究の対応する著者

研究成果: Article査読

39 被引用数 (Scopus)

抄録

Exercise is known to induce the oxidation of blood low-molecular-weight (LMW) thiols such as reduced glutathione (GSH). We previously reported that full-marathon running induced a decrease in human plasma levels of protein-bound sulfhydryl groups (p-SHs). Moderate exercise, a 30-min running at the intensity of the individual ventilatory threshold, performed by untrained healthy females caused a significant decrease in erythrocyte levels of p-SHs (mostly hemoglobin cysteine residues) and LMW thiols, but their levels returned to each baseline by 2 h. No significant change in plasma LMW thiols was observed. However, plasma levels of p-SHs significantly decreased after running and remained unchanged after 24 h. These results suggest that moderate exercise causes the oxidation of blood thiols, especially protein-bound thiols.

本文言語English
ページ(範囲)2039-2046
ページ数8
ジャーナルLife Sciences
70
17
DOI
出版ステータスPublished - 2002 3月 15
外部発表はい

ASJC Scopus subject areas

  • 薬理学

フィンガープリント

「Moderate physical exercise induces the oxidation of human blood protein thiols」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル