Molecular cloning of newt sex pheromone precursor cDNAs: Evidence for the existence of species-specific forms of pheromones

T. Iwata, K. Umezawa, F. Toyoda, N. Takahashi, H. Matsukawa, K. Yamamoto, S. Miura, H. Hayashi, S. Kikuyama

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    Cloning of cDNA encoding a decapeptide pheromone (sodefrin) that attracts conspecific female newts was attempted. A cDNA clone encoding a protein consisting of 189 amino acid residues including a sodefrin sequence was isolated from a Cynops pyrrhogaster abdominal gland cDNA library. Likewise, a cDNA clone encoding a molecule comparable to the sodefrin precursor was obtained from a Cynops ensicauda abdominal gland cDNA library. This clone encoded a precursor protein of 192 amino acid residues, including a sodefrin-like peptide sequence with substitutions of two amino acid residues. This is the first report of a peptide pheromone precursor in vertebrates. Copyright (C) 1999 Federation of European Biochemical Societies.

    元の言語English
    ページ(範囲)400-404
    ページ数5
    ジャーナルFEBS Letters
    457
    発行部数3
    DOI
    出版物ステータスPublished - 1999 9 3

    ASJC Scopus subject areas

    • Biochemistry
    • Biophysics
    • Molecular Biology

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    Iwata, T., Umezawa, K., Toyoda, F., Takahashi, N., Matsukawa, H., Yamamoto, K., Miura, S., Hayashi, H., & Kikuyama, S. (1999). Molecular cloning of newt sex pheromone precursor cDNAs: Evidence for the existence of species-specific forms of pheromones. FEBS Letters, 457(3), 400-404. https://doi.org/10.1016/S0014-5793(99)01062-5