Morphological approach for the functional improvement of an artificial myocardial assist device using shape memory alloy fibres

Y. Shiraishi*, T. Yambe, Y. Saijo, F. Sato, A. Tanaka, M. Yoshizawa, D. Ogawa, Y. Wada, S. Itoh, R. Sakata, Y. Park, M. Uematsu, M. Umezu, T. Fujimoto, N. Masumoto, H. Liu, A. Baba, S. Konno, S. Nitta, K. ImachiK. Tabayashi, H. Sasada, D. Homma

*この研究の対応する著者

研究成果: Conference contribution

9 被引用数 (Scopus)

抄録

The authors have been developing a mechano-electric artificial myocardial assist system (artificial myocardium) which is capable of supporting natural contractile functions from the outside of the ventricle without blood contacting surface. In this study, a nano-tech covalent type shape memory alloy fibre (Biometal, Toki Corp, Japan) was employed and the parallel-link structured myocardial assist device was developed. And basic characteristics of the system were examined in a mechanical circulatory system as well as in animal experiments using goats. The contractile functions were evaluated with the mock circulatory system that simulated systemic circulation with a silicone left ventricular model and an aortic afterload. Hemodynamic performance was also examined in goats. Prior to the measurement, the artificial myocardial assist device was installed into the goat's thoracic cavity and attached onto the ventricular wall. As a result, the system could be installed successfully without severe complications related to the heating, and the aortic flow rate was increased by 15% and the systolic left ventricular pressure was elevated by 7% under the cardiac output condition of 3L/min in a goat. And those values were elevated by the improvement of the design which was capable of the natural morphological myocardial tissue streamlines. Therefore it was indicated that the effective assistance might be achieved by the contraction by the newly-designed artificial myocardial assist system using Biometal. Moreover it was suggested that the assistance gain might be obtained by the optimised configuration design along with the natural anatomical myocardial stream line.

本文言語English
ホスト出版物のタイトル29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07
ページ3974-3977
ページ数4
DOI
出版ステータスPublished - 2007
イベント29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07 - Lyon, France
継続期間: 2007 8 232007 8 26

出版物シリーズ

名前Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
ISSN(印刷版)0589-1019

Conference

Conference29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07
国/地域France
CityLyon
Period07/8/2307/8/26

ASJC Scopus subject areas

  • 信号処理
  • 生体医工学
  • コンピュータ ビジョンおよびパターン認識
  • 健康情報学

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