The motor protein called kinesin transports membrane vesicle filled with neurotransmitters along the microtubules have the potential to form large structures by self-assembly. The kinesin allows the movement after taking it out of the cells and the system with a configuration reversed from the configuration are used conventionally. Tracks are created in the glass surface by lithography to succeed the microtubule movement to one dimension. The caged peptides are activated by ultraviolet irradiation, which identified a peptide that inhibited the motor activity of kinesin reversibly and developed a system that stops microtubular movement reversibly by ultraviolet irradiation that uncages the peptides. A more biological approach is to modify motile biological structures and use them as pre-assembled motile units in an artificial environment, rather than using purified motor proteins as nano-components of micro devices.
|ジャーナル||AIST Today (International Edition)|
|出版ステータス||Published - 2007 6|
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