Multi-modal 3D imaging of radionuclides using multiple hybrid Compton cameras

Akihisa Omata*, Miho Masubuchi, Nanase Koshikawa, Jun Kataoka, Hiroki Kato, Atsushi Toyoshima, Takahiro Teramoto, Kazuhiro Ooe, Yuwei Liu, Keiko Matsunaga, Takashi Kamiya, Tadashi Watabe, Eku Shimosegawa, Jun Hatazawa

*この研究の対応する著者

研究成果: Article査読

抄録

For radiological diagnosis and radionuclide therapy, X-ray and gamma-ray imaging technologies are essential. Single-photon emission tomography (SPECT) and positron emission tomography (PET) play essential roles in radiological diagnosis, such as the early detection of tumors. Radionuclide therapy is also rapidly developing with the use of these modalities. Nevertheless, a limited number of radioactive tracers are imaged owing to the limitations of the imaging devices. In a previous study, we developed a hybrid Compton camera that conducts simultaneous Compton and pinhole imaging within a single system. In this study, we developed a system that simultaneously realizes three modalities: Compton, pinhole, and PET imaging in 3D space using multiple hybrid Compton cameras. We achieved the simultaneous imaging of Cs-137 (Compton mode targeting 662 keV), Na-22 (PET mode targeting 511 keV), and Am-241 (pinhole mode targeting 60 keV) within the same field of view. In addition, the imaging of Ga-67 and In-111, which are used in various diagnostic scenarios, was conducted. We also verified that the 3D distribution of the At-211 tracer inside a mouse could be imaged using the pinhole mode.

本文言語English
論文番号2546
ジャーナルScientific reports
12
1
DOI
出版ステータスPublished - 2022 12月

ASJC Scopus subject areas

  • 一般

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