Newly identified repeat sequences, derived from human chromosome 21qter, are also localized in the subtelomeric region of particular chromosomes and 2q13, and are conserved in the chimpanzee genome

H. S. Park, M. Nogami, K. Okumura, Masahira Hattori, Y. Sakaki, A. Fujiyama*

*この研究の対応する著者

研究成果: Article査読

6 被引用数 (Scopus)

抄録

Subtelomeric regions have been a target of structural and functional studies of human chromosomes. Markers having a defined structure are especially useful to such studies. Here, we report 93 bp tandem repeat sequences found in the subtelomeric region of human chromosome 21q. They were also detected in the telomeric region of several other chromosomes. Interestingly, the repeat was also found in the 2q13 region which is known to be a position of chromosomal fusion, a major difference between the human and chimpanzee karyotypes. To the best of our knowledge, this repetitive sequence is a new member of human subtelomeric interspersed repeats. (C) 2000 Federation of European Biochemical Societies.

本文言語English
ページ(範囲)167-169
ページ数3
ジャーナルFEBS Letters
475
3
DOI
出版ステータスPublished - 2000 6 23
外部発表はい

ASJC Scopus subject areas

  • 生化学
  • 生物理学
  • 分子生物学

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