Nickel-catalyzed C-H/C-O coupling of azoles with phenol derivatives

Kei Muto, Junichiro Yamaguchi, Kenichiro Itami

研究成果: Article

265 被引用数 (Scopus)

抄録

The first nickel-catalyzed C-H bond arylation of azoles with phenol derivatives is described. The new Ni(cod) 2/dcype catalytic system is active for the coupling of various phenol derivatives such as esters, carbamates, carbonates, sulfamates, triflates, tosylates, and mesylates. With this C-H/C-O biaryl coupling, we synthesized a series of privileged 2-arylazoles, including biologically active alkaloids. Moreover, we demonstrated the utility of the present reaction for functionalizing estrone and quinine.

本文言語English
ページ(範囲)169-172
ページ数4
ジャーナルJournal of the American Chemical Society
134
1
DOI
出版ステータスPublished - 2012 1 11
外部発表はい

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

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