抄録
Nickel-catalyzed cross-coupling reactions have recently been receiving significant attention from the synthetic community as a way to construct carbon-carbon or carbon-heteroatom bonds, because nickel catalysts are less expensive and less toxic than palladium catalysts. We herein describe our recent developments in nickel-catalyzed biaryl coupling methodology, along with mechanistic studies and applications to the synthesis of natural products and pharmaceuticals. In particular, we focus on nickel-catalyzed direct coupling reactions in which "unreactive" bonds such as C-H, C-O, and C-C bonds are converted into biaryl moieties.
| 元の言語 | English |
|---|---|
| ページ（範囲） | 576-587 |
| ページ数 | 12 |
| ジャーナル | Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry |
| 巻 | 71 |
| 発行部数 | 6 |
| DOI | |
| 出版物ステータス | Published - 2013 |
| 外部発表 | Yes |
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ASJC Scopus subject areas
- Organic Chemistry
これを引用
Nickel-catalyzed direct coupling of heteroarenes. / Yamaguchi, Junichiro; Muto, Kei; Amaike, Kazuma; Yamamoto, Takuya; Itami, Kenichiro.
：: Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry, 巻 71, 番号 6, 2013, p. 576-587.研究成果: Article
}
TY - JOUR
T1 - Nickel-catalyzed direct coupling of heteroarenes
AU - Yamaguchi, Junichiro
AU - Muto, Kei
AU - Amaike, Kazuma
AU - Yamamoto, Takuya
AU - Itami, Kenichiro
PY - 2013
Y1 - 2013
N2 - Nickel-catalyzed cross-coupling reactions have recently been receiving significant attention from the synthetic community as a way to construct carbon-carbon or carbon-heteroatom bonds, because nickel catalysts are less expensive and less toxic than palladium catalysts. We herein describe our recent developments in nickel-catalyzed biaryl coupling methodology, along with mechanistic studies and applications to the synthesis of natural products and pharmaceuticals. In particular, we focus on nickel-catalyzed direct coupling reactions in which "unreactive" bonds such as C-H, C-O, and C-C bonds are converted into biaryl moieties.
AB - Nickel-catalyzed cross-coupling reactions have recently been receiving significant attention from the synthetic community as a way to construct carbon-carbon or carbon-heteroatom bonds, because nickel catalysts are less expensive and less toxic than palladium catalysts. We herein describe our recent developments in nickel-catalyzed biaryl coupling methodology, along with mechanistic studies and applications to the synthesis of natural products and pharmaceuticals. In particular, we focus on nickel-catalyzed direct coupling reactions in which "unreactive" bonds such as C-H, C-O, and C-C bonds are converted into biaryl moieties.
KW - C-H arylation
KW - Cross-coupling
KW - Febuxostat
KW - Heterobiaryl
KW - Muscoride A
KW - Nickel
KW - Tafamidis
KW - Texaline
KW - Texamine
UR - http://www.scopus.com/inward/record.url?scp=84884307061&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84884307061&partnerID=8YFLogxK
U2 - 10.5059/yukigoseikyokaishi.71.576
DO - 10.5059/yukigoseikyokaishi.71.576
M3 - Article
VL - 71
SP - 576
EP - 587
JO - Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry
JF - Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry
SN - 0037-9980
IS - 6
ER -