Nickel-catalyzed direct coupling of heteroarenes

Junichiro Yamaguchi, Kei Muto, Kazuma Amaike, Takuya Yamamoto, Kenichiro Itami

研究成果: Article

5 引用 (Scopus)

抄録

Nickel-catalyzed cross-coupling reactions have recently been receiving significant attention from the synthetic community as a way to construct carbon-carbon or carbon-heteroatom bonds, because nickel catalysts are less expensive and less toxic than palladium catalysts. We herein describe our recent developments in nickel-catalyzed biaryl coupling methodology, along with mechanistic studies and applications to the synthesis of natural products and pharmaceuticals. In particular, we focus on nickel-catalyzed direct coupling reactions in which "unreactive" bonds such as C-H, C-O, and C-C bonds are converted into biaryl moieties.

元の言語English
ページ(範囲)576-587
ページ数12
ジャーナルYuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry
71
発行部数6
DOI
出版物ステータスPublished - 2013
外部発表Yes

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Nickel
Carbon
Catalysts
Poisons
Palladium
Biological Products
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Organic Chemistry

これを引用

Nickel-catalyzed direct coupling of heteroarenes. / Yamaguchi, Junichiro; Muto, Kei; Amaike, Kazuma; Yamamoto, Takuya; Itami, Kenichiro.

:: Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry, 巻 71, 番号 6, 2013, p. 576-587.

研究成果: Article

Yamaguchi, Junichiro ; Muto, Kei ; Amaike, Kazuma ; Yamamoto, Takuya ; Itami, Kenichiro. / Nickel-catalyzed direct coupling of heteroarenes. :: Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry. 2013 ; 巻 71, 番号 6. pp. 576-587.
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