NiFe-layered double hydroxide sheets as an efficient electrochemical biosensing platform

Noel Nesakumar, Sengeni Anantharaj, Nandhini Subramanian, Subrata Kundu, Subbiah Alwarappan

研究成果: Article査読

10 被引用数 (Scopus)


The maximum allowed limits of chlorpromazine (CPZ) established by Food and Drug Administration (FDA) for children aged between 1 and 5 years is 0.125 mM and between 6 to 12 years is 0.235 mM. However, excess consumption of CPZ beyond these permissible limit cause adverse health effects. In order to detect CPZ, herein, we employ NiFe-layered double hydroxide sheets modified glassy carbon electrode (GC/NiFe LDH). The GC/NiFe LDH electrode exhibited a good electrocatalytic activity towards CPZ detection at a less working potential even in the presence of interferents such as ascorbic acid, uric acid, glucose, sucrose, fructose and acetaminophen. The anodic peak observed at 614 mV (vs. Ag/AgCl) corresponds to the oxidation of CPZ and the proposed platform exhibited an excellent linearity in the range 75 μM to 1.0 mM. Further, the GC/NiFe LDH electrode exhibited an excellent sensitivity (1.05 μA μM−1), repeatability (0.86% RSD), reproducibility (1.54% RSD) and limit of detection (1.23 μM).

ジャーナルJournal of the Electrochemical Society
出版ステータスPublished - 2018

ASJC Scopus subject areas

  • 電子材料、光学材料、および磁性材料
  • 再生可能エネルギー、持続可能性、環境
  • 表面、皮膜および薄膜
  • 電気化学
  • 材料化学


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