Non-invasive assessment of cardiac output during exercise in healthy young humans: Comparison between Modelflow method and Doppler echocardiography method

J. Sugawara, T. Tanabe, M. Miyachi, K. Yamamoto, K. Takahashi, M. Iemitsu, T. Otsuki, S. Homma, S. Maeda, R. Ajisaka, M. Matsuda*

*この研究の対応する著者

研究成果査読

167 被引用数 (Scopus)

抄録

Aims: The Modelflow method can estimate cardiac output from arterial blood pressure waveforms using a three-element model of aortic input impedance (aortic characteristic impedance, arterial compliance, and systemic vascular resistance). We tested the reliability of a non-invasive cardiac output estimation during submaximal exercise using the Modelflow method from finger arterial pressure waveforms collected by Portapres in healthy young humans. Methods: The Doppler echocardiography method was used as a reference method. Sixteen healthy young subjects (nine males and seven females) performed a multi-stage cycle ergometer exercise at an intensity corresponding to 70, 90, 110 and 130% of their individual ventilatory threshold for 2 min each. The simultaneous estimation of cardiac output (15 s averaged data) using the Modelflow and Doppler echocardiography methods was performed at rest and during exercise. Results and Conclusion: The Modelflow-estimated cardiac output correlated significantly with the simultaneous estimates by the Doppler method in all subjects (r = 0.87, P < 0.0001) and the SE of estimation was 1.93 L min-1. Correlation coefficients in each subject ranged from 0.91 to 0.98. Although the Modelflow method overestimated cardiac output, the errors between two estimates were not significantly different among the exercise levels. These results suggest that the Modelflow method using Portapres could provide a reliable estimation of the relative change in cardiac output non-invasively and continuously during submaximal exercise in healthy young humans, at least in terms of the relative changes in cardiac output.

本文言語English
ページ(範囲)361-366
ページ数6
ジャーナルActa Physiologica Scandinavica
179
4
DOI
出版ステータスPublished - 2003 12
外部発表はい

ASJC Scopus subject areas

  • 生理学

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