Noninvasive measurement of total hemoglobin and hemoglobin derivatives using multiwavelength pulse spectrophotometry -In vitro study with a mock circulatory system-

Hironori Suzaki, Naoki Kobayashi, Takashi Nagaoka, Kiyotaka Iwasaki, Mitsuo Umezu, Sunao Takeda, Tatsuo Togawa

研究成果: Conference contribution

21 被引用数 (Scopus)

抄録

Total hemoglobin (tHb), carboxyhemoglobin (COHb), and methemoglobin (MetHb) are usually measured with a CO-oximeter. Noninvasive and continuous measurement of these blood components is expected to decrease the pain of a patient. Therefore, we developed an instrument to measure oxygen saturation (SpO 2), tHb, COHb, and MetHb non-invasively. Multiwavelength LED (600, 625, 660, 760, 800, 940, and 1300 nm) and a combined detector (Si, InGaAs) were built into the instrument (Seven wavelengths transparent pulse spectrophotometer). We used the Waseda mock circulatory system, which can simulate blood circulation in tissues and generate a pulse wave mechanically, to estimate the instrument's performance. Furthermore we proposed new calculation formula including DC components of optical density (this method). Under conditions without any change of other components, the mean error ± standard deviation between this method and the CO-oximetry were SaO 2=0.0±1.4%, tHb=0.0±0.0 g/dl, COHb=0.0±2.0%, and MetHb=0.0±0.3%. When the concentration of other components was changed, this method showed mean errors and standard deviations of SaO 2=0.2±1.6%, tHb=0.0±0.4 g/dl, COHb=0.5±4.1%, and MetHb=0.0±0.3%.

本文言語English
ホスト出版物のタイトル28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06
ページ799-802
ページ数4
DOI
出版ステータスPublished - 2006 12 1
イベント28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06 - New York, NY, United States
継続期間: 2006 8 302006 9 3

出版物シリーズ

名前Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
ISSN(印刷版)0589-1019

Conference

Conference28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06
国/地域United States
CityNew York, NY
Period06/8/3006/9/3

ASJC Scopus subject areas

  • 信号処理
  • 生体医工学
  • コンピュータ ビジョンおよびパターン認識
  • 健康情報学

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