Nonlinear characteristics of visual evoked potential in glaucoma patients and their correlation with the visual responses on magnocellular and parvocellular pathways

Keiko Momose*, Motohiro Kiyosawa

*この研究の対応する著者

研究成果: Conference contribution

抄録

Purpose was to investigate the linear and nonlinear characteristics of VEPs, and their correlation with the visual parvocellular and magnocellular systems. The VEPs were elicited by pseudorandom luminance modulated stimulation from patients with primary open angle glaucoma and compared with normal subjects. VEPs were recorded from 26 eyes with primary open angle glaucoma (POAG) and 10 eyes of age-matched normal volunteers. To acquire the VEPs, the eye was stimulated with a pseudorandom binary sequence (PRBS) stimulus of 40 sec duration. The first (linear) and second-order (nonlinear) binary kernels were determined by a cross-correlation function between PRBS and VEP. The amplitudes of the first- and second-order kernels decreased with the advancement of POAG. Positive peak latencies around 120 ms of first slice of second-order kernels increased with the advancement of POAG, while the second slice amplitudes were not different in normal, early POAG and moderate POAG patients. These results support the observations in previous studies that the first and second slice response functions reflect the response of the M- and P-pathways, respectively.

本文言語English
ホスト出版物のタイトル28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06
ページ4568-4571
ページ数4
DOI
出版ステータスPublished - 2006
イベント28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06 - New York, NY, United States
継続期間: 2006 8 302006 9 3

出版物シリーズ

名前Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
ISSN(印刷版)0589-1019

Conference

Conference28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06
国/地域United States
CityNew York, NY
Period06/8/3006/9/3

ASJC Scopus subject areas

  • 信号処理
  • 生体医工学
  • コンピュータ ビジョンおよびパターン認識
  • 健康情報学

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