### 抄録

This report presents a proposal of a new technique to estimate the cross-sectional absorption distribution of turbid media from backscattered light by solving a nonlinear inverse problem. After illuminating a beam of light on the surface of a turbid object and measuring the backscattered light as a function of distance from the light incident point, we divide the object into multiple virtual layers to estimate the absorption distribution. The path lengths of photon propagation in the respective layers are calculated using Monte Carlo simulation. The absorption coefficient of each virtual layer can be estimated from the backscattered intensity and the path length distribution in a depth direction. For solving this inverse problem, the linear calculation results are useful as initial solutions. Then the final solutions are obtained from iteration of the nonlinear calculation. Convergence into a unique solution and robustness of the solution against the measurement noise were confirmed. The effectiveness of the proposed technique was verified through simulation and measurement. By lateral scanning of a source–detector pair, we can reconstruct a cross-sectional image of the turbid medium to the depth to which the detected light reaches.

元の言語 | English |
---|---|

記事番号 | 105891 |

ジャーナル | Optics and Lasers in Engineering |

巻 | 126 |

DOI | |

出版物ステータス | Published - 2020 3 |

### Fingerprint

### ASJC Scopus subject areas

- Electronic, Optical and Magnetic Materials
- Atomic and Molecular Physics, and Optics
- Mechanical Engineering
- Electrical and Electronic Engineering

### これを引用

*Optics and Lasers in Engineering*,

*126*, [105891]. https://doi.org/10.1016/j.optlaseng.2019.105891

**Nonlinear inversion technique for absorption tomography of turbid media using spatially resolved backscattered light.** / Nishida, Kazuhiro; Kato, Yuji; Kudo, Nobuki; Shimizu, Koichi.

研究成果: Article

*Optics and Lasers in Engineering*, 巻. 126, 105891. https://doi.org/10.1016/j.optlaseng.2019.105891

}

TY - JOUR

T1 - Nonlinear inversion technique for absorption tomography of turbid media using spatially resolved backscattered light

AU - Nishida, Kazuhiro

AU - Kato, Yuji

AU - Kudo, Nobuki

AU - Shimizu, Koichi

PY - 2020/3

Y1 - 2020/3

N2 - This report presents a proposal of a new technique to estimate the cross-sectional absorption distribution of turbid media from backscattered light by solving a nonlinear inverse problem. After illuminating a beam of light on the surface of a turbid object and measuring the backscattered light as a function of distance from the light incident point, we divide the object into multiple virtual layers to estimate the absorption distribution. The path lengths of photon propagation in the respective layers are calculated using Monte Carlo simulation. The absorption coefficient of each virtual layer can be estimated from the backscattered intensity and the path length distribution in a depth direction. For solving this inverse problem, the linear calculation results are useful as initial solutions. Then the final solutions are obtained from iteration of the nonlinear calculation. Convergence into a unique solution and robustness of the solution against the measurement noise were confirmed. The effectiveness of the proposed technique was verified through simulation and measurement. By lateral scanning of a source–detector pair, we can reconstruct a cross-sectional image of the turbid medium to the depth to which the detected light reaches.

AB - This report presents a proposal of a new technique to estimate the cross-sectional absorption distribution of turbid media from backscattered light by solving a nonlinear inverse problem. After illuminating a beam of light on the surface of a turbid object and measuring the backscattered light as a function of distance from the light incident point, we divide the object into multiple virtual layers to estimate the absorption distribution. The path lengths of photon propagation in the respective layers are calculated using Monte Carlo simulation. The absorption coefficient of each virtual layer can be estimated from the backscattered intensity and the path length distribution in a depth direction. For solving this inverse problem, the linear calculation results are useful as initial solutions. Then the final solutions are obtained from iteration of the nonlinear calculation. Convergence into a unique solution and robustness of the solution against the measurement noise were confirmed. The effectiveness of the proposed technique was verified through simulation and measurement. By lateral scanning of a source–detector pair, we can reconstruct a cross-sectional image of the turbid medium to the depth to which the detected light reaches.

KW - Backscattered light

KW - Biomedical applications

KW - Nonlinear inverse problem

KW - Optical computed tomography

KW - Spatially resolved measurement

UR - http://www.scopus.com/inward/record.url?scp=85073479477&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85073479477&partnerID=8YFLogxK

U2 - 10.1016/j.optlaseng.2019.105891

DO - 10.1016/j.optlaseng.2019.105891

M3 - Article

AN - SCOPUS:85073479477

VL - 126

JO - Optics and Lasers in Engineering

JF - Optics and Lasers in Engineering

SN - 0143-8166

M1 - 105891

ER -