Novel metabolic pathway for salicylate biodegradation via phenol in yeast Trichosporon moniliiforme

Yuichiro Iwasaki, Hiroaki Gunji, Kuniki Kino, Takasumi Hattori, Yoshitaka Ishii, Kohtaro Kirimura

研究成果: Article

20 引用 (Scopus)

抜粋

A novel metabolic pathway was found in the yeast Trichosporon moniliiforme WU-0401 for salicylate degradation via phenol as the key intermediate. When 20 mM salicylate was used as the sole carbon source for the growth of strain WU-0401, phenol was detected as a distinct metabolite in the culture broth. Analysis of the products derived from salicylate or phenol through reactions with resting cells and a cell-free extract of strain WU-0401 indicated that salicylate is initially decarboxylated to phenol and then oxidized to catechol, followed by aromatic ring cleavage to form cis-cis muconate.

元の言語English
ページ(範囲)557-564
ページ数8
ジャーナルBiodegradation
21
発行部数4
DOI
出版物ステータスPublished - 2010 7 1

ASJC Scopus subject areas

  • Environmental Engineering
  • Microbiology
  • Bioengineering
  • Environmental Chemistry
  • Pollution

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